Comparative Effectiveness of SNAGs Versus NAGs in Reducing Pain and Increasing Chest Mobility in Kyphoscoliosis Patients with Parkinsonism
DOI:
https://doi.org/10.61919/dgmzrg93Keywords:
Parkinsonism, kyphoscoliosis, SNAGs, NAGs, manual therapy, pain reduction, chest mobility, randomized controlled trial.Abstract
Background: Kyphoscoliosis is a complex spinal deformity commonly associated with Parkinsonism, leading to impaired postural alignment, restricted chest expansion, pain, and diminished quality of life. Manual therapy techniques such as Sustained Natural Apophyseal Glides (SNAGs) and Natural Apophyseal Glides (NAGs) are frequently employed for musculoskeletal disorders but their comparative effectiveness in Parkinsonism-related kyphoscoliosis remains unclear. Objective: To compare the short-term effects of SNAGs and NAGs on pain reduction and chest mobility in patients with Parkinsonism and kyphoscoliosis. Methods: In this double-blind randomized controlled trial, 60 patients with Parkinsonism and kyphoscoliosis were randomly assigned to either SNAGs (n=30) or NAGs (n=30) groups. Interventions were administered three times per week for four weeks. Primary outcomes included change in pain intensity, assessed by the Visual Analog Scale (VAS), and chest mobility, measured as thoracic expansion. Between-group differences were analyzed using independent t-tests with 95% confidence intervals. Results: Both groups demonstrated significant within-group improvements in pain and chest expansion. The SNAGs group achieved greater reductions in VAS scores (–3.1 ± 0.4) compared to the NAGs group (–1.5 ± 0.5; p=0.001), and greater increases in chest mobility (+1.7 ± 0.3 cm vs. +0.8 ± 0.3 cm; p<0.001). A moderate positive correlation was observed between pain reduction and chest mobility improvement in the SNAGs group (r=0.46). Conclusion: SNAGs are more effective than NAGs in reducing pain and improving chest mobility in patients with Parkinsonism-related kyphoscoliosis, supporting their preferential use in rehabilitation practice.
References
1. Jankovic J, Lang AE. Diagnosis and assessment of Parkinson disease and other movement disorders. In: Bradley’s Neurology in Clinical Practice E-Book. 2021;24:310–33.
2. Rawat CS, Pandey S. Parkinson’s disease–an introduction. In: Techniques for assessment of Parkinsonism for diagnosis and rehabilitation. Springer; 2021. p. 1–24.
3. Mostoufi SA, George TK, Mostoufi Y. Spinal Deformities: Kyphosis and Scoliosis. In: Clinical Guide to Musculoskeletal Medicine: A Multidisciplinary Approach. Springer; 2022. p. 91–9.
4. Al-Wardat M, Geroin C, Schirinzi T, Etoom M, Tinazzi M, Pisani A, et al. Axial postural abnormalities and pain in Parkinson’s disease. J Neural Transm. 2023;130(2):77–85.
5. Saifee T, Farmer S, Shah S, Choi D. Spinal column and spinal cord disorders. In: Neurology: a queen square textbook. 2024. p. 463–98.
6. Afolayan JO, Shafafy R, Maher M, Moon KH, Panchmatia JR. Assessment and management of adult spinal deformities. Br J Hosp Med (Lond). 2018;79(2):79–85.
7. Praud J-P, Redding GJ. Chest wall and respiratory muscle disorders. In: Kendig’s disorders of the respiratory tract in children. Elsevier; 2019. p. 1044–61.e2.
8. Patel N, Howard IM, Baydur A. Respiratory considerations in patients with neuromuscular disorders. Muscle Nerve. 2023;68(2):122–41.
9. Rana AQ, Qureshi ARM, Haris A, Danish MA, Furqan MS, Shaikh O, et al. Negative impact of severity of pain on mood, social life and general activity in Parkinson’s disease. Neurol Res. 2018;40(12):1054–9.
10. Docu Axelerad A, Stroe AZ, Arghir OC, Docu Axelerad D, Gogu AE. Respiratory dysfunctions in Parkinson’s disease patients. Brain Sci. 2021;11(5):595.
11. Tueth LE, Duncan RP. Musculoskeletal pain in Parkinson’s disease: a narrative review. Neurodegener Dis Manag. 2021;11(5):373–85.
12. Kumar S, Goyal L, Singh S. Tremor and rigidity in patients with Parkinson’s disease: emphasis on epidemiology, pathophysiology and contributing factors. CNS Neurol Disord Drug Targets. 2022;21(7):596–609.
13. Athanasiadis D, Dionyssiotis Y, Krumov J, Obretenov V, Panayotov K, Papathanasiou J. The cognitive-behavioral aspects of the Mulligan concept of manual therapy: a systematic review. Eur J Transl Myol. 2022;32(2):10504.
14. Saleem I, Zahoor IA, Rana AA, Sarfraz S, Ibrahim M, Ghaffar N. Comparison of Sustained Natural Apophyseal Glide and Natural Apophyseal Glide effects on pain, range of motion and neck disability in patients with chronic neck pain. Pak J Health Sci. 2022:154–8.
15. Palakurthi B, Burugupally SP. Postural instability in Parkinson’s disease: a review. Brain Sci. 2019;9(9):239.
16. El Gendy MH, Mohamed SR, Taman SE, Hussein HM, Abu El Kasem ST. Short term effect of spinal mobilization with movement on pulmonary functions in nonsmokers with thoracic hyperkyphosis: a randomized single-blinded controlled trial. J Man Manip Ther. 2023;31(2):64–71.
17. Kim J, Cho J. Effectiveness of mid thoracic spine mobilization on postural balance and gait ability in subacute stroke patients: a randomized clinical trial. J Back Musculoskelet Rehabil. 2024;37(1):233–40.
18. Szewczyk D, Sadura-Sieklucka T, Tarnacka B, Targowski T. Influence of manual therapy and stretching exercises on mobility status and pulmonary function tests among patients with ankylosing spondylitis. Med Rehabil. 2023;27:60–5.
19. El Hayek M, Lopes JLMLJ, LeLaurin JH, Gregory ME, Abi Nehme A-M, McCall-Junkin P, et al. Type, timing, frequency, and durability of outcome of physical therapy for Parkinson disease: a systematic review and meta-analysis. JAMA Netw Open. 2023;6(7):e2324860.
20. Ellis TD, Colón-Semenza C, DeAngelis TR, Thomas CA, Saint Hilaire M-H, Earhart GM, et al. Evidence for early and regular physical therapy and exercise in Parkinson's disease. Semin Neurol. 2021;41(4):414–23.
21. Johnson R, Chen S, Lewis J. Comparative efficacy of sustained manual therapy techniques for chronic low back pain: a systematic review. J Orthop Sports Phys Ther. 2023;53(2):97–108.
22. Miller D, Thompson B. Mobilization techniques and spinal degeneration: clinical impact review. Phys Ther Rev. 2021;26(1):12–9.
23. Adams M, Bogduk N, Burton K, Dolan P. The biomechanics of back pain. 3rd ed. Edinburgh: Churchill Livingstone; 2020.
24. El Gendy MH, Hussein HM. Mobilization interventions for thoracic dysfunction: a clinical overview. J Man Manip Ther. 2023;31(3):101–10.
25. Mulligan BR. Manual therapy: the Mulligan Concept. 2nd ed. Oxford: Butterworth-Heinemann; 2020.
26. Boutron I, Moher D, Altman DG, Schulz KF, Ravaud P. Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration. Ann Intern Med. 2008;148(4):295–309.
27. Kim J, Cho J, Park S. Spine mobilization and rehabilitation outcomes in neurodegenerative diseases: a systematic review. J Back Musculoskelet Rehabil. 2024;37(2):301–12.
28. Saleem I, Khan MA, Zahoor IA. Manual therapy in postural disorders: comparative effectiveness review. Pak J Health Sci. 2022;4(1):77–83.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Sumaira Nawaz, Eenara Hasan, Sayeda Ansa Gillani, Mohammed Fadl Rasheed, Kainat Sheikh, Hassan Javed (Author)

This work is licensed under a Creative Commons Attribution 4.0 International License.