Comparison of Bone Graft with Plate vs Zero-Profile PEEK Cage for Anterior Cervical Discectomy and Fusion

Authors

  • Ghulam Mustafa Bolan Medical College, Quetta, Pakistan Author
  • Abid Hussain Bolan Medical College, Quetta, Pakistan Author
  • Wazir Ahmed Department of Orthopaedic Surgery, Bolan Medical College, Quetta, Pakistan Author
  • Raz Muhammad Bazai Bolan Medical College, Quetta, Pakistan Author
  • Sher Hassan Khan Bolan Medical College, Quetta, Pakistan Author
  • Muhammad Mujahid Sharif Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan Author

DOI:

https://doi.org/10.61919/t0nj3997

Keywords:

ACDF, PEEK cage, anterior cervical plate, spinal fusion, cervical disc herniation, functional outcomess

Abstract

Background: Anterior cervical discectomy and fusion (ACDF) is a widely used procedure for cervical disc disease, employing either bone graft with anterior plating or zero-profile PEEK cages. While both approaches aim to achieve spinal stability and neural decompression, their comparative effectiveness in clinical and operative outcomes remains under debate. Objective: To compare the radiological and clinical outcomes of ACDF using bone graft with anterior plate versus zero-profile PEEK cage. Methods: This prospective comparative study enrolled 60 patients with cervical disc herniation who underwent single- or two-level ACDF. Group A received bone graft with anterior plate, while Group B received zero-profile PEEK cages. Outcomes assessed at 3 and 6 months included fusion rates, disc height, segmental lordosis, Neck Disability Index (NDI), Visual Analog Scale (VAS) scores, operative time, and intraoperative blood loss. Statistical analysis was performed using SPSS v25.0 with a significance level of p < 0.05. Results: Fusion rates were similar between groups (93.3% vs. 86.7%, p = 0.38). Group A showed better lordosis (p = 0.02), while Group B had lower NDI (p = 0.00), neck pain (p = 0.04), operative time (p = 0.00), and blood loss (p = 0.00). Conclusion: Both ACDF techniques are effective, but zero-profile PEEK cages offer superior clinical recovery, reduced invasiveness, and operative efficiency.

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Published

2025-07-17

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Articles

How to Cite

1.
Ghulam Mustafa, Abid Hussain, Wazir Ahmed, Raz Muhammad Bazai, Sher Hassan Khan, Muhammad Mujahid Sharif. Comparison of Bone Graft with Plate vs Zero-Profile PEEK Cage for Anterior Cervical Discectomy and Fusion. JHWCR [Internet]. 2025 Jul. 17 [cited 2025 Aug. 24];:e609. Available from: https://jhwcr.com/index.php/jhwcr/article/view/609

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