Role of MRI in Characterizing Spine and Spinal Cord Tumors Based on Anatomical Level, Tumor Position, Lesion Length, Cord Expansion, and Morphological MRI Features
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Abstract
Background: Spine and spinal cord tumors are clinically important lesions because delayed recognition may lead to pain, sensory disturbance, myelopathy, neurological disability, and functional decline. Magnetic resonance imaging is the principal modality for evaluating these tumors because it provides detailed visualization of tumor compartment, cord morphology, margins, and adjacent structural involvement. Objective: To describe the role of conventional MRI in characterizing spine and spinal cord tumors according to anatomical and morphological imaging features in adult patients. Methods: This prospective descriptive cross-sectional observational study was conducted at Lahore General Hospital over 90 days after synopsis approval. Sixty adult patients aged 18 years and above with spine or spinal cord tumors and complete preoperative MRI studies were included. MRI was performed using conventional T1-weighted, T2-weighted, STIR, and post-contrast T1-weighted sequences. Clinical symptoms and MRI features, including cord expansion, lesion morphology, margin definition, tumor compartment, bone involvement, and disc involvement, were analyzed descriptively using SPSS version 27.0. Results: The mean age was 47.68 ± 15.81 years, and females comprised 53.3% of participants. Numbness was reported in 51.7%, loss of sensation in 50.0%, and lower back pain and radiating pain each in 48.3%. Extradural location was recorded in 53.3%, bone and disc involvement each in 51.7%, well-defined margins in 50.0%, and cord expansion and intramedullary location each in 48.3%. Conclusion: Conventional MRI provided useful anatomical and morphological characterization of spine and spinal cord tumors, particularly for identifying tumor compartment, cord expansion, lesion margins, and adjacent bone or disc involvement. Further studies with histopathological correlation and standardized reporting are needed
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