Mothers’ Perceptions of Childhood Vaccination Barriers in Rural Communities of Pakistan: A Comprehensive Qualitative Study

Main Article Content

Sibghat Ullah
Dua Tahir
Iqra Tahir
Mehak Wasif
Zulfiqar Ali
Javairia Saleh

Abstract

Background: Childhood immunization remains suboptimal in rural Pakistan despite established national programs. Sociocultural norms, gender dynamics, and health system constraints contribute to missed or delayed vaccination. Qualitative evidence is needed to understand maternal perspectives and decision-making processes. Objective: To explore mothers’ perceptions of childhood vaccination and identify sociocultural, behavioral, and health system barriers influencing immunization uptake in rural Pakistan Methods: A qualitative interpretative endline study was conducted in rural districts of Punjab and Sindh. Data were collected through in-depth interviews (n=30) and focus group discussions (n=5) with mothers of children under five years. Interviews were conducted in local languages, audio-recorded, transcribed, and analyzed using inductive thematic analysis. Results: Six major themes emerged: knowledge gaps and misconceptions; sociocultural and community influences; gendered decision-making and limited maternal autonomy; accessibility and health system barriers; trust and communication with healthcare providers; and fear of side effects. Vaccination behavior was shaped by interacting factors rather than isolated barriers. While most mothers expressed acceptance of vaccination, constraints related to mobility, service availability, and household decision-making led to delays, partial uptake, or missed vaccinations. Conclusion: Vaccination barriers in rural Pakistan are multidimensional and context-dependent. Interventions should prioritize community engagement, improved service delivery, male involvement, and strengthened provider communication to enhance immunization uptake.

Article Details

Section

Review Articles

How to Cite

1.
Sibghat Ullah, Dua Tahir, Iqra Tahir, Mehak Wasif, Zulfiqar Ali, Javairia Saleh. Mothers’ Perceptions of Childhood Vaccination Barriers in Rural Communities of Pakistan: A Comprehensive Qualitative Study. JHWCR [Internet]. 2026 Apr. 15 [cited 2026 Apr. 22];4(7):1-10. Available from: https://jhwcr.com/index.php/jhwcr/article/view/1484

References

1. World Health Organization. Immunization coverage. Geneva: WHO; 2020.

2. National Institute of Population Studies (NIPS) [Pakistan], ICF. Pakistan Demographic and Health Survey 2017–18. Islamabad, Pakistan; 2019.

3. United Nations Children’s Fund (UNICEF). Pakistan immunization report. Islamabad: UNICEF; 2022.

4. Expanded Programme on Immunization (EPI). Annual report. Islamabad, Pakistan; 2021.

5. Bhutta ZA, Das JK, Walker N, Rizvi A, Campbell H, Rudan I, et al. Interventions to address deaths from childhood pneumonia and diarrhoea equitably: what works and at what cost? Lancet. 2011;377(9763):403–12.

6. Hafeez A, Akram DS, Suhail A, Jan SS, Shaikh BT, Zafar S. Determinants of vaccination coverage in Pakistan: evidence from secondary data analysis. J Pak Med Assoc. 2011;61(3):210–5.

7. Sadaf A, Richards JL, Glanz J, Salmon DA, Omer SB. A systematic review of interventions for reducing parental vaccine refusal and hesitancy. Vaccine. 2013;31(40):4293–304.

8. Kok MC, Dieleman M, Taegtmeyer M, Broerse JE, Kane SS, Ormel H, et al. Which intervention design factors influence performance of community health workers? A systematic review. Health Policy Plan. 2015;30(9):1207–27.

9. Nishtar S, Boerma T, Amjad S, Alam AY, Khalid F, Haq I, et al. Pakistan’s health system: performance and prospects after the 18th Constitutional Amendment. Lancet. 2013;381(9885):219–30.

10. Glenton C, Lewin S, Scheel IB. Still too little qualitative research to shed light on results from reviews of effectiveness trials: a case study of a Cochrane review on vaccination communication. Health Res Policy Syst. 2011;9:53.

11. Opel DJ, Mangione-Smith R, Taylor JA, Korfiatis C, Wiese C, Catz S, et al. Development of a survey to identify vaccine-hesitant parents: the Parent Attitudes about Childhood Vaccines survey. Pediatrics. 2011;128(5):e1120–7.

12. MacDonald NE; SAGE Working Group on Vaccine Hesitancy. Vaccine hesitancy: definition, scope and determinants. Vaccine. 2015;33(34):4161–4.

13. Larson HJ, Jarrett C, Eckersberger E, Smith DM, Paterson P. Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: a systematic review of published literature, 2007–2012. Vaccine. 2014;32(19):2150–9.

14. Dubé E, Laberge C, Guay M, Bramadat P, Roy R, Bettinger JA. Vaccine hesitancy: an overview. Hum Vaccin Immunother. 2013;9(8):1763–73.

15. Brown KF, Kroll JS, Hudson MJ, Ramsay M, Green J, Vincent CA, et al. Factors underlying parental decisions about combination childhood vaccinations including MMR: a systematic review. Vaccine. 2010;28(26):4235–48.

16. Muzammil M, et al. Barriers to universal health coverage in Pakistan: a health system perspective. [Unpublished/Report]; 2025.

17. World Health Organization Strategic Advisory Group of Experts (SAGE). Report of the SAGE working group on vaccine hesitancy. Geneva: WHO; 2014.