Frequency and Etiology of Hematemesis in Patients Presenting to the Emergency Department

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Dr. Moazzam Farooq
Dr. Farhan Ali
Afifa Nighat
Dr. Muhammad Haseeb
Dr. Leena Siddiqui
Arshad Ullah
Dr. Wali Ullah

Abstract

Background: Hematemesis is an important manifestation of upper gastrointestinal bleeding requiring prompt stabilization and identification of the bleeding source because management differs substantially between variceal and non-variceal causes. Objective: To determine the frequency and etiological distribution of hematemesis among patients presenting to the emergency department. Methods: This prospective observational study included 100 consecutive patients aged 15–80 years presenting with hematemesis to the Emergency Department of Lady Reading Hospital–Medical Teaching Institution, Peshawar, Pakistan, from 1 January to 30 June 2026. Clinical characteristics and relevant laboratory findings were recorded, and upper gastrointestinal endoscopy was performed after stabilization to establish the bleeding etiology. Data were analysed using IBM SPSS Statistics version 26.0 and summarized descriptively. Results: The mean age was 46.8 ± 16.7 years, with an observed range of 18–80 years; 68 (68.0%) participants were male. Esophageal varices were the most frequent etiology, occurring in 42 (42.0%) patients, followed by peptic ulcer disease in 25 (25.0%), erosive gastritis in 12 (12.0%), gastric varices in 8 (8.0%), Mallory–Weiss tear in 5 (5.0%), esophagitis in 4 (4.0%), and upper gastrointestinal malignancy in 4 (4.0%). Variceal and non-variceal causes each accounted for 50 (50.0%) cases. Chronic liver disease was documented in 55 (55.0%) patients, NSAID use in 28 (28.0%), and previous upper gastrointestinal bleeding in 21 (21.0%). The mean interval from emergency presentation to endoscopy was 18.6 ± 7.4 hours. Conclusion: Variceal bleeding, particularly esophageal varices, and peptic ulcer disease constituted the principal etiologies of hematemesis in this emergency department population. Recognition of the local etiological pattern and timely endoscopic assessment are important components of appropriate clinical management

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How to Cite

[1]
Dr. Moazzam Farooq et al. 2026. Frequency and Etiology of Hematemesis in Patients Presenting to the Emergency Department. Journal of Health, Wellness and Community Research. 4, 2 (Jan. 2026), 1–7. DOI:https://doi.org/10.61919/cmj31879.

References

1. Feldman M, Friedman LS, Brandt LJ, editors. Sleisenger and Fordtran's gastrointestinal and liver disease. 11th ed. Philadelphia: Elsevier; 2021.

2. Gralnek IM, Stanley AJ, Morris AJ, Camus M, Lau J, Lanas A, et al. Endoscopic diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH): European Society of Gastrointestinal Endoscopy (ESGE) Guideline—Update 2021. Endoscopy. 2021;53(3):300–332.

3. Lanas A, Dumonceau JM, Hunt RH, Fujishiro M, Scheiman JM, Gralnek IM, et al. Non-variceal upper gastrointestinal bleeding. Nat Rev Dis Primers. 2018;4:18020.

4. Laine L, Barkun AN, Saltzman JR, Martel M, Leontiadis GI. ACG Clinical Guideline: Upper gastrointestinal and ulcer bleeding. Am J Gastroenterol. 2021;116(5):899–917.

5. Barkun AN, Almadi M, Kuipers EJ, Laine L, Sung J, Tse F, et al. Management of nonvariceal upper gastrointestinal bleeding: guideline recommendations from the International Consensus Group. Ann Intern Med. 2019;171(11):805–822.

6. Stanley AJ, Laine L. Management of acute upper gastrointestinal bleeding. BMJ. 2019;364:l536.

7. de Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C; Baveno VII Faculty. Baveno VII—Renewing consensus in portal hypertension. J Hepatol. 2022;76(4):959–974.

8. Sarin SK, Kumar A, Angus PW, et al. Diagnosis and management of portal hypertension and variceal bleeding: Asian Pacific Association recommendations. Hepatol Int. 2022;16:1–35.

9. World Health Organization. Global progress report on HIV, viral hepatitis and sexually transmitted infections. Geneva: World Health Organization; 2021.

10. Hreinsson JP, Kalaitzakis E, Gudmundsson S, Björnsson ES. Upper gastrointestinal bleeding: incidence, etiology and outcomes in a population-based setting. Scand J Gastroenterol. 2013;48(4):439–447.

11. Someili A, Mobarki S, Moafa R, Alsury L, Shadad RHM, Fathi S, et al. Upper gastrointestinal bleeding: a retrospective, single-center experience on the role of endoscopy and outcomes. J Clin Med Res. 2025;17:22–32. doi:10.14740/jocmr6134.

12. Lee H, Chung JW, Kim KO, Kwon KA, Kim JH. Changing epidemiology and etiology of upper gastrointestinal bleeding. Korean J Gastroenterol. 2025. doi:10.4166/kjg.2025.080.

13. Mujadzic H, Noorani S, Riddle PJ, Wang Y, Metts G, Yacu T, et al. Ulcer bleeding in the United States: epidemiology, treatment success, and resource utilization. Dig Dis Sci. 2024. doi:10.1007/s10620-024-08322-y.