Effectiveness of Mobilization with Movement Versus Proprioceptive Neuromuscular Facilitation Hold-Relax Technique on Pain and Functional Mobility in Patients with Chronic Knee Osteoarthritis: A Randomized Controlled Trial

Main Article Content

Aafeen Maham
Hamid Ali
Mohammad Jawad Khan
Iqrash Fatima
Saira Muzaffar Shah
Soom Khalil

Abstract

Background: Knee osteoarthritis is a common degenerative musculoskeletal disorder associated with pain, stiffness, reduced mobility, and functional limitation. Manual therapy and neuromuscular facilitation techniques are frequently used in conservative rehabilitation, but direct comparative evidence between Mobilization with Movement and Proprioceptive Neuromuscular Facilitation Hold-Relax remains limited. Objective: To compare the short-term effectiveness of Mobilization with Movement and Proprioceptive Neuromuscular Facilitation Hold-Relax on pain, stiffness, physical function, and total WOMAC score in patients with chronic knee osteoarthritis. Methods: This randomized controlled trial was conducted at Khan Rehab Centre, Haleema Siraj Hospital, Rawalpindi, from 1 August 2021 to 31 January 2022. Thirty patients aged 40–60 years with chronic knee osteoarthritis were recruited through convenience sampling and randomized into two groups. Group A received Mobilization with Movement with conventional exercises, while Group B received PNF Hold-Relax with the same conventional program. Outcomes were assessed using WOMAC at baseline and after two weeks. Results: Group A showed reductions in pain, stiffness, physical function, and total WOMAC scores of 66.0%, 60.8%, 52.2%, and 55.0%, respectively, while Group B showed reductions of 56.0%, 53.5%, 50.1%, and 51.4%. Pain differed significantly between groups post-intervention, favouring Group A, while stiffness, physical function, and total WOMAC were comparable. Conclusion: Both interventions improved WOMAC outcomes, but Mobilization with Movement showed a greater short-term pain reduction.

Article Details

Section

Articles

How to Cite

1.
Aafeen Maham, Hamid Ali, Mohammad Jawad Khan, Iqrash Fatima, Saira Muzaffar Shah, Soom Khalil. Effectiveness of Mobilization with Movement Versus Proprioceptive Neuromuscular Facilitation Hold-Relax Technique on Pain and Functional Mobility in Patients with Chronic Knee Osteoarthritis: A Randomized Controlled Trial. JHWCR [Internet]. 2026 Apr. 29 [cited 2026 Apr. 29];4(8):1-7. Available from: https://jhwcr.com/index.php/jhwcr/article/view/1526

References

1. Garstang SV, Stitik TP. Osteoarthritis: epidemiology, risk factors, and pathophysiology. Am J Phys Med Rehabil. 2006;85(11 Suppl):S2-S11.

2. Glyn-Jones S, Palmer AJR, Agricola R, Price AJ, Vincent TL, Weinans H, et al. Osteoarthritis. Lancet. 2015;386(9991):376-387.

3. Mora JC, Przkora R, Cruz-Almeida Y. Knee osteoarthritis: pathophysiology and current treatment modalities. J Pain Res. 2018;11:2189-2196.

4. Bannuru RR, Schmid CH, Kent DM, Vaysbrot EE, Wong JB, McAlindon TE. Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis. Ann Intern Med. 2015;162(1):46-54.

5. Heidari B. Knee osteoarthritis diagnosis, treatment and associated factors of progression: part II. Caspian J Intern Med. 2011;2(3):249-255.

6. Sinusas K. Osteoarthritis: diagnosis and treatment. Am Fam Physician. 2012;85(1):49-56.

7. Decary S, Ouellet P, Vendittoli PA, Desmeules F. Reliability of physical examination tests for the diagnosis of knee disorders: evidence from a systematic review. Man Ther. 2016;26:172-182.

8. Kulkarni AV, Kamat MM. A study to determine the effectiveness of mobilization with movement techniques in knee osteoarthritis pain. Int J Health Sci Res. 2017;7(4).

9. Ringdahl E, Pandit S. Treatment of knee osteoarthritis. Am Fam Physician. 2011;83(11):1287-1292.

10. Masekar B, Rayjade DA, Yadav DT, Chotai DK. Effectiveness of muscle energy technique and proprioceptive neuromuscular facilitation in knee osteoarthritis. Int J Pharma Bio Sci. 2021;11(1):16-22.

11. Mehmood Z, Anwar N, Tauqeer S, Shabbir M, Khalid K, Mehmood S. Comparison of Maitland mobilization and Mulligan mobilization with movement in knee osteoarthritis patients. Pak J Med Res. 2021;60(3):126-130.

12. Ghanbari A, Ebrahimian M, Mohamadi M, Najjar-Hasanpour A. Comparing hold relax-proprioceptive neuromuscular facilitation and static stretching techniques in management of hamstring tightness. Indian J Physiother Occup Ther. 2013;7(1):126.

13. Weleslassie GG, Temesgen MH, Alamer A, Tsegay GS, Hailemariam TT, Melese H. Effectiveness of mobilization with movement on the management of knee osteoarthritis: a systematic review of randomized controlled trials. Pain Res Manag. 2021;2021.

14. Nathani S, Tank KD. Effect of PNF stretching on proprioception and physical function in individual with knee osteoarthritis: an experimental study. Int J Sci Healthc Res. 2020;11(7):779.

15. Gupta R, Heggannavar A. Quantitative effects of proprioceptive exercises and Mulligan’s mobilization with movement in subjects with osteoarthritis knee: a randomized controlled trial. Int J Ther Rehabil Res. 2015;4(4):191.

16. Kiran A, Ijaz MJ, Qamar MM, Basharat A, Rasul A, Ahmed W. Comparison of efficacy of Mulligan’s mobilization with movement with Maitland mobilization along with conventional therapy in patients with knee osteoarthritis: a randomized clinical trial. Libyan Int Med Univ J. 2018;3(1):26.

17. Halimah A, Muthiah S. The different effect of hold relax and contract relax on pain and range of motion in knee joint osteoarthritis. Urban Health. 2021;3(1).